Native Human Apotransferrin

Cat.No.: TF-103H
Product Overview: Native Human Apotransferrin was purified from Human Plasma.
Description: This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
Source: Human Plasma
Species: Human
Form: Lyophilized from 10 mM phosphate buffer, pH 7.4.
Molecular Mass: 80 kDa
Purity: ≥95% by SDS-PAGE
Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Storage: Store at -20°C.
Gene Name: TF transferrin [ Homo sapiens ]
Official Symbol: TF
Synonyms: TF; transferrin; serotransferrin; PRO1557; PRO2086; siderophilin; beta-1 metal-binding globulin; TFQTL1; DKFZp781D0156;
Gene ID: 7018
mRNA Refseq: NM_001063
Protein Refseq: NP_001054
MIM: 190000
UniProt ID: P02787
Chromosome Location: 3q21
Pathway: EPHB forward signaling, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Hemostasis, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem;
Function: ferric iron binding; metal ion binding; protein binding; ubiquitin protein ligase binding;

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