Recombinant Human RAPGEF6, GST-tagged
Cat.No. : | RAPGEF6-1632H |
Product Overview : | Recombinant Human RAPGEF6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-164aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 [ Homo sapiens ] |
Official Symbol : | RAPGEF6 |
Synonyms : | RAPGEF6; Rap guanine nucleotide exchange factor (GEF) 6; PDZ domain containing guanine nucleotide exchange factor (GEF) 2 , PDZGEF2; rap guanine nucleotide exchange factor 6; PDZ GEF2; RA GEF 2; PDZ domain-containing guanine nucleotide exchange factor 2; PDZ domain-containing guanine nucleotide exchange factor I; PDZ domain containing guanine nucleotide exchange factor (GEF) 2; RAGEF2; PDZGEF2; KIA001LB; PDZ-GEF2; RA-GEF-2; DKFZp667N084; DKFZp686I15116; |
Gene ID : | 51735 |
mRNA Refseq : | NM_001164386 |
Protein Refseq : | NP_001157858 |
MIM : | 610499 |
UniProt ID : | - |
Chromosome Location : | 5q31.1 |
Function : | GTP-dependent protein binding; Ras GTPase binding; guanyl-nucleotide exchange factor activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionAnimal models, such as mice with RAPGEF6 gene mutations, are being used to study the impact of RAPGEF6 dysfunction on neurological development and behavior.
RAPGEF6 protein is involved in the regulation of neuronal differentiation, axon guidance, and synaptic plasticity, contributing to proper brain development and function.
Targeting RAPGEF6 protein or its downstream signaling pathways may hold therapeutic potential for certain neurological conditions, but specific interventions are still under investigation.
Genetic testing, such as whole exome sequencing, is employed to identify mutations in the RAPGEF6 gene that may be linked to neurological disorders.
RAPGEF6 has been shown to interact with various proteins involved in synaptic transmission and neuronal signaling, suggesting potential implications in neurological disorders.
Customer Reviews (3)
Write a reviewthe RAPGEF6 protein's high quality and its compatibility with my experimental needs, coupled with the manufacturer's excellent technical support, create a valuable alliance that contributes to successful research endeavors.
The RAPGEF6 protein is characterized by its exceptional quality, making it an ideal choice to fulfill my experimental requirements.
The manufacturer's commitment to providing high-quality proteins is evident in their meticulous production process, ensuring the purity and reliability of the RAPGEF6 protein.
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