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Recombinant Human IL33, His-tagged

Cat.No. : IL33-59H
Product Overview : Recombinant Human IL33 (aa 1-270), fused at the C-terminus to a His-tag, was expressed in E. coli.
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Description : IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. 0.2µm-filtered solution in 55mM TRIS-HCl, pH 8.2, containing 150mM sodium chloride.
Endotoxin : <1.0EU/µg purified protein (LAL test)
Purity : ≥90% (SDS-PAGE)
Storage : -20°C
Concentration : 0.25mg/ml
Gene Name : IL33 interleukin 33 [ Homo sapiens (human) ]
Official Symbol : IL33
Synonyms : IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2; interleukin 33; interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules
Gene ID : 90865
mRNA Refseq : NM_001199640
Protein Refseq : NP_001186569
MIM : 608678
UniProt ID : O95760
Chromosome Location : 9p24.1
Pathway : Cytosolic DNA-sensing pathway; Influenza A
Function : cytokine activity; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Which immune cells can recombinant IL33 be used to detect? 05/28/2022

It can be used to detect immune cells such as macrophages and dendritic cells.

In what research fields can recombinant IL33 be applied? 09/24/2020

This protein applied in immunology, drug research, life science and other fields.

What is the action mechanism of IL33? 08/09/2020

Regulates the activity of immune cells by binding to receptors to stimulate the production of inflammatory factors such as interferon and TNF-α.

Besides treating asthma and hay fever, what other diseases can be treated with IL33? 07/28/2019

IL33 can also be used to treat a variety of inflammatory diseases, such as inflammatory bowel disease, psoriasis and so on.

How to prepare IL33? 03/25/2019

The preparation of IL33 requires first cloning the IL33 gene into the expression vector, and then the expression vector is expressed and purified in the cell culture medium.

How long does it take to treat asthma with IL33? 01/10/2019

Treating asthma with recombinant IL33 takes several weeks to several months to be effective, depending on the severity of the condition and the individual patient.

Customer Reviews (3)

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Reviews
10/16/2021

    Good solubility and is easy to operate and purify.

    05/03/2021

      Effectively mimics the function of the target protein in vitro.

      03/18/2020

        IL33 has a wide range of applications in the field of scientific research and is suitable for a variety of experimental design and research purposes.

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