Recombinant Human RNF168, GST-tagged
Cat.No. : | RNF168-2338H |
Product Overview : | Recombinant Human RNF168 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-351aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | RNF168 ring finger protein 168, E3 ubiquitin protein ligase [ Homo sapiens ] |
Official Symbol : | RNF168 |
Synonyms : | RNF168; ring finger protein 168, E3 ubiquitin protein ligase; ring finger protein 168; E3 ubiquitin-protein ligase RNF168; FLJ35794; FLJ39749; |
Gene ID : | 165918 |
mRNA Refseq : | NM_152617 |
Protein Refseq : | NP_689830 |
MIM : | 612688 |
UniProt ID : | Q8IYW5 |
Chromosome Location : | 3q29 |
Function : | chromatin binding; histone binding; ligase activity; metal ion binding; protein binding; ubiquitin binding; ubiquitin-protein ligase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
Rnf168-5551M | Recombinant Mouse Rnf168 Protein, Myc/DDK-tagged | +Inquiry |
RNF168-30H | Recombinant Human RNF168, GST-tagged | +Inquiry |
RNF168-679H | Recombinant Human RNF168 Protein, MYC/DDK-tagged | +Inquiry |
RNF168-0038H | Recombinant Human RNF168 Protein (Met1-Lys571), N-His-tagged | +Inquiry |
RNF168-0039H | Recombinant Human RNF168 Protein (Asn523-Arg565), N-His-tagged | +Inquiry |
◆ Lysates | ||
RNF168-1520HCL | Recombinant Human RNF168 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionClinical trials investigating the potential use of RNF168 as a target for cancer therapy or as a biomarker for cancer prognosis may be underway, but specific details would need to be checked.
RNF168 plays a role in initiating a signaling cascade that leads to the recruitment of other DNA repair proteins to the site of DNA damage, promoting repair and maintaining genomic stability.
RNF168 interacts with various proteins involved in the DNA damage response, such as 53BP1 and BRCA1, to coordinate the repair of DNA lesions and maintain genomic stability.
Yes, inherited mutations in the RNF168 gene can increase the risk of developing certain cancers, particularly those associated with DNA damage and repair deficiencies.
The potential side effects and toxicities of targeting RNF168 in cancer therapy are still being explored, and would depend on the specific approach and modality used.
Customer Reviews (3)
Write a reviewNot only does it provide reliable and consistent results due to its high quality and purity, but it also holds significant value in understanding cellular processes and disease mechanisms.
This commitment to excellence ensures that researchers are provided with the most advanced and reliable tools for their investigations.
the RNF168 protein offers numerous advantages in trials and research experiments.
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