Recombinant Human SORD, His-tagged
Cat.No. : | SORD-2878H |
Product Overview : | Recombinant Human SORD protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-357aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | SORD sorbitol dehydrogenase [ Homo sapiens ] |
Official Symbol : | SORD |
Synonyms : | SORD; sorbitol dehydrogenase; L-iditol 2-dehydrogenase; SORD1; |
Gene ID : | 6652 |
mRNA Refseq : | NM_003104 |
Protein Refseq : | NP_003095 |
MIM : | 182500 |
UniProt ID : | Q00796 |
Chromosome Location : | 15q15-q21.1 |
Pathway : | Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; sorbitol degradation I, organism-specific biosystem; |
Function : | L-iditol 2-dehydrogenase activity; L-iditol 2-dehydrogenase activity; NAD binding; metal ion binding; oxidoreductase activity; sugar binding; zinc ion binding; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
SORD-8575M | Recombinant Mouse SORD Protein, His (Fc)-Avi-tagged | +Inquiry |
SORD-701C | Recombinant Cynomolgus Monkey SORD Protein, His (Fc)-Avi-tagged | +Inquiry |
Sord-6046M | Recombinant Mouse Sord Protein, Myc/DDK-tagged | +Inquiry |
SORD-5330R | Recombinant Rat SORD Protein, His (Fc)-Avi-tagged | +Inquiry |
SORD-4224R | Recombinant Rhesus Macaque SORD Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SORD-1569HCL | Recombinant Human SORD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionAt present, the association between SORD protein and disease is not well understood, and further research is needed to explore its role in specific diseases.
SORD protein is involved in the antioxidant process in cells, and may indirectly affect the antioxidant capacity in cells by regulating heptitol-6-phosphate metabolism.
There is no clear information on the association between SORD protein mutations and inherited diseases.
There is no evidence that the lack of SORD protein function directly leads to the development of disease. However, it may affect the normal function of the glucose metabolism pathway.
The protein may play a role in metabolic pathways related to metabolic diseases (e.g., diabetes mellitus and metabolic syndrome), but the specific relationship still needs to be further studied.
SORD protein is involved in the heptylol-6-phosphoreductase reaction in the glucose metabolism pathway, which converts heptitol-6-phosphate to cholesterol alcohol.
Customer Reviews (3)
Write a reviewThe stability of SORD products allows them to cope with different experimental conditions and modes of operation.
SORD has a high specific activity and can exert strong biological effects at low concentrations.
When experiments were performed with SORD, the reproducibility of the results was excellent.
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