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Recombinant Human TSG101 protein, His-sumo/Myc-tagged

Cat.No. : TSG101-3445H
Product Overview : Recombinant Human TSG101(2-390 aa) fused with His-sumo tag at C-terminal and Myc tag at N-terminal was expressed in E. coli.
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Description : This protein belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Source : E. coli
Species : Human
Tag : His-sumo/Myc
Form : Tris-based buffer, 50% glycerol
Protein length : 2-390 aa
AA Sequence : AVSESQLKK MVSKYKYRDL TVRETVNVIT LYKDLKPVLD SYVFNDGSSR ELMNLTGTIP VPYRGNTYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP QSDLLGLIQV MIVVFGDEPP VFSRPISASY PPYQATGPPN TSYMPGMPGG ISPYPSGYPP NPSGYPGCPY PPGGPYPATT SSQYPSQPPV TTVGPSRDGT ISEDTIRASL ISAVSDKLRW RMKEEMDRAQ AELNALKRTE EDLKKGHQKL EEMVTRLDQE VAEVDKNIEL LKKKDEELSS ALEKMENQSE NNDIDEVIIP TAPLYKQILN LYAEENAIED TIFYLGEALR RGVIDLDVFL KHVRLLSRKQ FQLRALMQKA RKTAGLSDLY
Purity : >85% (SDS-PAGE)
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Gene Name : TSG101 tumor susceptibility gene 101 [ Homo sapiens ]
Official Symbol : TSG101
Synonyms : TSG101; tumor susceptibility gene 101; TSG10, tumor susceptibility gene 10; tumor susceptibility gene 101 protein; VPS23; tumor susceptibility protein; ESCRT-I complex subunit TSG101; TSG10;
Gene ID : 7251
mRNA Refseq : NM_006292
Protein Refseq : NP_006283
MIM : 601387
UniProt ID : Q99816

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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07/01/2022

    Exemplifying professionalism, the manufacturer excels in delivering truly exceptional quality.

    10/03/2020

      The consistent quality of your protein reagents gives me peace of mind.

      06/13/2020

        My satisfaction knows no bounds when it comes to the peerless quality and performance of this protein reagent.

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