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Recombinant Human WNT5B, StrepII-tagged

Cat.No. : WNT5B-207H
Product Overview : Purified, full-length human recombinant WNT5B protein (amino acids 18-359, 342 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 38.5 kDa. (Accession NP_110402.2; UniProt Q9H1J7)
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  • Gene Information
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Description : Wnt5B is a ligand for members of the frizzled family of seven transmembrane receptors. It is a probable developmental protein and may be a signaling molecule which affects the development of discrete regions of tissues. It is likely to signal over only few cell diameters. The protein belongs to the Wnt family.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free).
Protein length : 18-359, 342 a.a.
AA Sequence : QLLTDANSWWSLALNPVQRPEMFII GAQPVCSQLPGLSPGQRKLCQLYQE HMAYIGEGAKTGIKECQHQFRQRRW NCSTADNASVFGRVMQIGSRETAFT HAVSAAGVVNAISRACREGELSTCG CSRTARPKDLPRDWLWGGCGDNVEY GYRFAKEFVDAREREKNFAKGSEEQ GRVLMNLQNNEAGRRAVYKMADVAC KCHGVSGSCSLKTCWLQLAEFRKVG DRLKEKYDSAAAMRVTRKGRLELVN SRFTQPTPEDLVYVDPSPDYCLRNE STGSLGTQGRLCNKTSEGMDGCELM CCGRGYNQFKSVQVERCHCKFHWCC FVRCKKCTEIVDQYICK
Endotoxin : <0.1 eu per ug protein by lal
Purity : >95% pure by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.
Gene Name : WNT5B wingless-type MMTV integration site family, member 5B [ Homo sapiens ]
Official Symbol : WNT5B
Synonyms : WNT5B; wingless-type MMTV integration site family, member 5B; protein Wnt-5b; WNT-5B protein; MGC2648;
Gene ID : 81029
mRNA Refseq : NM_030775
Protein Refseq : NP_110402
MIM : 606361
UniProt ID : Q9H1J7
Chromosome Location : 12p13.3
Pathway : Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Hedgehog signaling pathway, organism-specific biosystem;
Function : frizzled-2 binding; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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