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Recombinant Human WNT8B, StrepII-tagged

Cat.No. : WNT8B-210H
Product Overview : Purified, full-length human recombinant WNT8B protein (amino acids 23-351, 329 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 35.2 kDa. (Accession NP_003384.2; UniProt Q93098)
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Description : Wnt8b is a ligand for members of the frizzled family of seven transmembrane receptors. It may play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free).
Protein length : 23-351, 329 a.a.
AA Sequence : WSVNNFLMTGPKAYLIYSSSVAAGA QSGIEECKYQFAWDRWNCPERALQL SSHGGLRSANRETAFVHAISSAGVM YTLTRNCSLGDFDNCGCDDSRNGQL GGQGWLWGGCSDNVGFGEAISKQFV DALETGQDARAAMNLHNNEAGRKAV KGTMKRTCKCHGVSGSCTTQTCWLQ LPEFREVGAHLKEKYHAALKVDLLQ GAGNSAAGRGAIADTFRSISTRELV HLEDSPDYCLENKTLGLLGTEGREC LRRGRALGRWERRSCRRLCGDCGLA VEERRAETVSSCNCKFHWCCAVRCE QCRRRVTKYFCSRAERPRGGAAHKP GRKP
Endotoxin : <0.1 eu per ug protein by lal
Purity : >95% pure by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.
Gene Name : WNT8B wingless-type MMTV integration site family, member 8B [ Homo sapiens ]
Official Symbol : WNT8B
Synonyms : WNT8B; wingless-type MMTV integration site family, member 8B; protein Wnt-8b;
Gene ID : 7479
mRNA Refseq : NM_003393
Protein Refseq : NP_003384
MIM : 601396
UniProt ID : Q93098
Chromosome Location : 10q24
Pathway : Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Hedgehog signaling pathway, organism-specific biosystem;
Function : G-protein coupled receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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