Recombinant Human IL2, StrepII-tagged
| Cat.No. : | IL2-219H |
| Product Overview : | Purified, full-length human recombinant Interleukin-2 or IL2 protein (amino acids 21-153, 133 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 15.4 kDa. (Accession NP_000577.2; UniProt P60568) |
- Specification
- Gene Information
- Related Products
| Description : | IL2 is produced by T-cells in response to antigenic or mitogenic stimulation and is required for T-cell proliferation and other activities crucial to regulation of the immune response. It stimulates B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. |
| Source : | Human Cells |
| Species : | Human |
| Tag : | StrepII |
| Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). |
| Protein length : | 21-153, 133 a.a. |
| AA Sequence : | APTSSSTKKTQLQLEHLLLDLQMIL NGINNYKNPKLTRMLTFKFYMPKKA TELKHLQCLEEELKPLEEVLNLAQS KNFHLRPRDLISNINVIVLELKGSE TTFMCEYADETATIVEFLNRWITFC QSIISTLT |
| Endotoxin : | <0.1 eu per ug protein by lal |
| Purity : | >95% pure by SDS-PAGE |
| Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
| Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. |
| Gene Name : | IL2 interleukin 2 [ Homo sapiens ] |
| Official Symbol : | IL2 |
| Synonyms : | IL2; interleukin 2; interleukin-2; IL 2; T cell growth factor; TCGF; aldesleukin; involved in regulation of T-cell clonal expansion; IL-2; lymphokine; |
| Gene ID : | 3558 |
| mRNA Refseq : | NM_000586 |
| Protein Refseq : | NP_000577 |
| MIM : | 147680 |
| UniProt ID : | P60568 |
| Chromosome Location : | 4q26-q27 |
| Pathway : | Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; |
| Function : | carbohydrate binding; cytokine activity; glycosphingolipid binding; growth factor activity; interleukin-2 receptor binding; interleukin-2 receptor binding; kappa-type opioid receptor binding; kinase activator activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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