| Cat.No. : |
MLH1-233H |
| Product Overview : |
Purified human recombinant DNA mismatch repair MLH1 protein (amino acids 410-652, 243 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 27.4 kDa. (Accession NP_000240.1; UniProt P40692) |
| Description : |
This product is a fragment of MLH1, which is a component of the post-replicative DNA mismatch repair system (MMR). It is a human homolog of the E. coli DNA mismatch repair gene mutL. Native MLH1 heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis. |
| Source : |
Human Cells |
| Species : |
Human |
| Tag : |
StrepII |
| Form : |
Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). |
| Protein length : |
410-652, 243 a.a. |
| AA Sequence : |
AIVTEDKTDI SSGRARQQDE EMLELPAPAE VAAKNQSLEG DTTKGTSEMS EKRGPTSSNP RKRHREDSDV EMVEDDSRKE MTAACTPRRR IINLTSVLSL QEEINEQGHE VLREMLHNHS FVGCVNPQWA LAQHQTKLYL LNTTKLSEEL FYQILIYDFA NFGVLRLSEP APLFDLAMLA LDSPESGWTE EDGPKEGLAE YIVEFLKKKA EMLADYFSLE IDEEGNLIGL PLLIDNYVPP LEG |
| Endotoxin : |
<0.1 eu per ug protein by lal |
| Purity : |
>95% pure by SDS-PAGE |
| Storage : |
12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
| Reconstitution : |
Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.