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Recombinant Human CD68, StrepII-tagged

Cat.No. : CD68-239H
Product Overview : Purified human recombinant CD68 or Macrosialin protein (amino acids 22-319, 298 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 31.5 kDa. (Accession NP_001242.2; UniProt P34810)
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Description : This product is the extracellular domain of CD68. CD68 is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free).
Protein length : 22-319, 298 a.a.
AA Sequence : NDCPHKKSATLLPSFTVTPTVTEST GTTSHRTTKSHKTTTHRTTTTGTTS HGPTTATHNPTTTSHGNVTVHPTSN STATSQGPSTATHSPATT SHGNATVHPTSNSTATSPGFTSSAH PEPPPPSPSPSPTSKETIGDYTWTN GSQPCVHLQAQIQIRVMYTTQGGGE AWGISVLNPNKTKVQGSCEGAHPH LLLSFPYGHLSFGFMQDLQQKVVYL SYMAVEYNVSFPHAAQWTFSAQNAS LRDLQAPLGQSFSCSNSSIILSPAV HLDLLSLRLQAAQLPHTGVFGQSFS C PSDRS
Endotoxin : <0.1 eu per ug protein by lal
Purity : >95% pure by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.
Gene Name : CD68 CD68 molecule [ Homo sapiens ]
Official Symbol : CD68
Synonyms : CD68; CD68 molecule; CD68 antigen; macrosialin; DKFZp686M18236; GP110; LAMP4; macrophage antigen CD68; SCARD1; scavenger receptor class D; member 1; scavenger receptor class D, member 1;
Gene ID : 968
mRNA Refseq : NM_001040059
Protein Refseq : NP_001035148
MIM : 153634
UniProt ID : P34810
Chromosome Location : 17p13
Pathway : Lysosome, organism-specific biosystem; Lysosome, conserved biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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