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Recombinant Human SPP1, StrepII-tagged

Cat.No. : SPP1-260H
Product Overview : Purified, full-length human recombinant OSTP (SPP1) or Osteopontin protein (amino acids 17-314, 298 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 33.7 kDa. (Accession NP_001035149.1; UniProt P10451)
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  • Gene Information
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Description : Osteopontin is involved in the attachment of osteoclasts to the mineralized bone matrix. It is secreted and binds hydroxyapatite with high affinity. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free).
Protein length : 17-314, 298 a.a.
AA Sequence : IPVKQADSGSSEEKQLYNKYPDAVA TWLNPDPSQKQNLLAPQNAVSSEET NDFKQETLPSKSNESHDHMDDMDDE DDDDHVDSQDSID SNDSDDVDDTDDSHQSDESHHSDES DELVTDFPTDLPATEVFTPVVPTVD TYDGRGDSVVYGLRSKSKKFRRPDI QYPDATDEDITSHMESEELNGAYKA I PVAQDLNAPSDWDSRGKDSYETSQL DDQSAETHSHKQSRLYKRKANDESN EHSDVIDSQELSKVSREFHSHEFHS HEDMLVVDPKSKEEDKHLKFRISHE LDSASSEVN
Endotoxin : <0.1 eu per ug protein by lal
Purity : >95% pure by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.
Gene Name : SPP1 secreted phosphoprotein 1 [ Homo sapiens ]
Official Symbol : SPP1
Synonyms : SPP1; secreted phosphoprotein 1; BNSP, bone sialoprotein I , OPN, osteopontin; osteopontin; BSPI; early T lymphocyte activation 1; ETA 1; uropontin; nephropontin; osteopontin-C; osteopontin-D; SPP1/CALPHA1 fusion; bone sialoprotein 1; urinary stone protein; early T-lymphocyte activation 1; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); OPN; BNSP; ETA-1; MGC110940;
Gene ID : 6696
mRNA Refseq : NM_000582
Protein Refseq : NP_000573
MIM : 166490
UniProt ID : P10451
Chromosome Location : 4q22.1
Pathway : Direct p53 effectors, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem;
Function : cytokine activity; extracellular matrix binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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