Recombinant Human IL10, StrepII-tagged
Cat.No. : | IL10-267H |
Product Overview : | Purified, full-length human recombinant IL10 protein (amino acids 19-178, 160 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 18.6 kDa. (Accession NP_000563; UniProt P22301) |
- Specification
- Gene Information
- Related Products
Description : | IL10 is a cytokine produced primarily by monocytes and, to a lesser extent, by lymphocytes. IL10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. It belongs to the IL10 family. |
Source : | Human Cells |
Species : | Human |
Tag : | StrepII |
Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). |
Protein length : | 19-178, 160 a.a. |
AA Sequence : | MHSSALLCCLVLLTGVRASPGQGTQ SENSCTHFPGNLPNMLRDLRDAFSR VKTFFQMKDQLDNLLLKESLLEDFK GYLGCQALSEMIQFYLEEVMPQAEN QDPDIKAHVNSLGENLKTLRLRLRR CHRFLPCENKSKAVEQVKNAFNKLQ EKGIYKAMSEFDIFINYIEAYMTMK IRN |
Endotoxin : | <0.1 eu per ug protein by lal |
Purity : | >80% by SDS-PAGE |
Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. |
Gene Name : | IL10 interleukin 10 [ Homo sapiens ] |
Official Symbol : | IL10 |
Synonyms : | IL10; interleukin 10; interleukin-10; CSIF; cytokine synthesis inhibitory factor; IL 10; IL10A; T cell growth inhibitory factor; TGIF; T-cell growth inhibitory factor; GVHDS; IL-10; MGC126450; MGC126451; |
Gene ID : | 3586 |
mRNA Refseq : | NM_000572 |
Protein Refseq : | NP_000563 |
MIM : | 124092 |
UniProt ID : | P22301 |
Chromosome Location : | 1q31-q32 |
Pathway : | African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Asthma, organism-specific biosystem; |
Function : | cytokine activity; growth factor activity; interleukin-10 receptor binding; |
Products Types
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il10-998Z | Recombinant Zebrafish il10 Protein, His-tagged | +Inquiry |
IL10-4400M | Recombinant Monkey IL10 Protein | +Inquiry |
◆ Lysates | ||
IL10-2079HCL | Recombinant Human IL10 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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