Recombinant Human IL5, StrepII-tagged
| Cat.No. : | IL5-269H |
| Product Overview : | Purified, full-length human recombinant IL5 protein (amino acids 20-134, 115 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 15.2 kDa. (Accession NP_000870; UniProt P05113) |
- Specification
- Gene Information
- Related Products
| Description : | IL5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for IL3 and colony stimulating factor 2 (CSF2/GM-CSF). |
| Source : | Human Cells |
| Species : | Human |
| Tag : | StrepII |
| Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). |
| Protein length : | 20-134, 115 a.a. |
| AA Sequence : | IPTEIPTSALVKETLALLSTHRTLL IANETLRIPVPVHKNHQLCTEEIFQ GIGTLESQTVQGGTVERLFKNLSLI KKYIDGQKKKCGEERRRVNQFLDYL QEFLGVMNTEWIIES |
| Endotoxin : | <0.1 eu per ug protein by lal |
| Purity : | >80~90%% by SDS-PAGE |
| Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
| Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. |
| Gene Name : | IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ] |
| Official Symbol : | IL5 |
| Synonyms : | IL5; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; B cell differentiation factor I; EDF; eosinophil differentiation factor; IL 5; interleukin 5; T cell replacing factor; TRF; T-cell replacing factor; B-cell differentiation factor I; IL-5; |
| Gene ID : | 3567 |
| mRNA Refseq : | NM_000879 |
| Protein Refseq : | NP_000870 |
| MIM : | 147850 |
| UniProt ID : | P05113 |
| Chromosome Location : | 5q23-q31 |
| Pathway : | Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; |
| Function : | cytokine activity; growth factor activity; interleukin-5 receptor binding; protein binding; |
Products Types
| ◆ Lysates | ||
| IL5-456CCL | Recombinant Canine IL5 cell lysate | +Inquiry |
| IL5-496MCL | Recombinant Mouse IL5 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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