Cat.No. : |
IL4-279H |
Product Overview : |
Purified, full-length human recombinant IL4 protein (amino acids 25-153, 129 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 17.5 kDa. (Accession NP_000580; UniProt P05112) |
Description : |
IL4 is a pleiotropic cytokine produced by activated T cells. It participates in several B-cell activation processes as well as of other cell types. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1, as well as regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. In addition, it is a costimulator of DNA-synthesis. |
Source : |
Human Cells |
Species : |
Human |
Tag : |
StrepII |
Form : |
Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free) |
Protein length : |
25-153, 129 a.a. |
AA Sequence : |
HKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHR HKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS |
Endotoxin : |
<0.1 eu per μg protein by lal |
Purity : |
>85% by SDS-PAGE |
Storage : |
12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles |
Reconstitution : |
Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml |