Recombinant Human CXCL2, StrepII-tagged
Cat.No. : | CXCL2-282H |
Product Overview : | Purified, full-length human recombinant GRO-beta (CXCL2) protein (amino acids 35-107, 73 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 7.9 kDa. (Accession NP_002080.1; UniProt P19875) |
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- Gene Information
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Description : | GRO-beta belongs to the intercine alpha (CXC chemokine) family. It is produced by activated monocytes and neutrophils and expressed at sites of inflammation. GRO-beta is available as an immunomodulator and is used prior to hematopoetic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy-induced cytopenias. |
Source : | Human Cells |
Species : | Human |
Tag : | StrepII |
Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free) |
Protein length : | 35-107, 73 a.a. |
AA Sequence : | APLATELRCQCLQTLQGIHLKNIQS VKVKSPGPHCAQTEVIATLKNGQKA CLNPASPMVKKIIEKMLKNGKSN |
Endotoxin : | <0.1 eu per μg protein by lal |
Purity : | >90% by SDS-PAGE |
Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml |
Gene Name : | CXCL2 chemokine (C-X-C motif) ligand 2 [ Homo sapiens ] |
Official Symbol : | CXCL2 |
Synonyms : | CXCL2; chemokine (C-X-C motif) ligand 2; GRO2, GRO2 oncogene; C-X-C motif chemokine 2; CINC 2a; GROb; MGSA b; MIP 2a; SCYB2; gro-beta; MGSA beta; MIP2-alpha; GRO2 oncogene; growth-regulated protein beta; macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; GRO2; MIP2; MIP2A; MGSA-b; MIP-2a; CINC-2a; |
Gene ID : | 2920 |
mRNA Refseq : | NM_002089 |
Protein Refseq : | NP_002080 |
MIM : | 139110 |
UniProt ID : | P19875 |
Chromosome Location : | 4q13.3 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response, organism-specific biosystem; |
Function : | chemokine activity; |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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