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Recombinant Human IFNL1, StrepII-tagged

Cat.No. : IFNL1-299H
Product Overview : Purified, full-length human recombinant IFNL1 (IL29) protein (amino acids 20-200, 181 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 20.0 kDa. (Accession NP_742152.1; UniProt Q8IU54)
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  • Gene Information
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Description : This is a cytokine distantly related to type I interferons and the IL-10 family. This protein, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free)
Protein length : 20-200, 181 a.a.
AA Sequence : GPVPTSKPTTTGKGCHIGRFKSLSP QELASFKKARDALEESLKLKNWSCS SPVFPGNWDLRLLQVRERPVALEAE LALTLKVLEAAAGPALEDVLDQPLH TLHHILSQLQACIQPQPTAGPRPRG RLHHWLHRLQEAPKKESAGCLEASV TFNLFRLLTRDLKYVADGNLCLRTS THPEST
Endotoxin : <0.1 eu per μg protein by lal
Purity : >90% by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for up to 1 month.
Gene Name : IL29 interleukin 29 (interferon, lambda 1) [ Homo sapiens ]
Official Symbol : IFNL1
Synonyms : IL29; interleukin 29 (interferon, lambda 1); interleukin 29; interleukin-29; IFNL1; IL 29; IFN-lambda-1; cytokine Zcyto21; interferon lambda-1; interferon-lambda-1; interferon, lambda 1; IL-29;
Gene ID : 282618
mRNA Refseq : NM_172140
Protein Refseq : NP_742152
MIM : 607403
UniProt ID : Q8IU54
Chromosome Location : 19q13.13
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine activity; interleukin-28 receptor binding; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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