Recombinant Human PLD3, GST-tagged
| Cat.No. : |
PLD3-105H |
| Product Overview : |
Recombinant Human PLD3(1 a.a. - 490 a.a.) , fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
| Description : |
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Source : |
Wheat germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
81.1 kDa |
| AA Sequence : |
MKPKLMYQELKVPAEEPANELPMNE IEAWKAAEKKARWVLLVLILAVVGF GALMTQLFLWEYGDLHLFGPNQRPA PCYDPCEAVLVESIPEGLDFPNAST GNPSTSQAWLGLLAGAHSSLDIASF YWTLTNNDTHTQEPSAQQGEEVLRQ LQTLAPKGVNVRIAVSKPSGPQPQA DLQALLQSGAQVRMVDMQKLTHGVL HTKFWVVDQTHFYLGSANMDWRSLT QVKELGVVMYNCSCLARDLTKIFEA YWFLGQAGSSIPSTWPRFYDTRYNQ ETPMEICLNGTPALAYLASAPPPLC PSGRTPDLKALLNVVDNARSFIYVA VMNYLPTLEFSHPHRFWPAIDDGLR RATYERGVKVRLLISCWGHSEPSMR AFLLSLAALRDNHTHSDIQVKLFVV PADEAQARIPYARVNHNKYMVTERA TYIGTSNWSGNYFTETAGTSLLVTQ NGRGGLRSQLEAIFLRDWDSPYSHD LDTSADSVGNACRLL |
| Applications : |
ELISA; WB-Re; AP; Array |
| Storage : |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Gene Name : |
PLD3 phospholipase D family, member 3 [ Homo sapiens (human) ] |
| Official Symbol : |
PLD3 |
| Synonyms : |
PLD3; HUK4; HU-K4; phospholipase D family, member 3; hospholipase D3; PLD 3; hindIII K4L homolog; choline phosphatase 3; phosphatidylcholine-hydrolyzing phospholipase D3; NP_001026866.1; EC 3.1.4.4; NP_036400.2 |
| Gene ID : |
23646 |
| mRNA Refseq : |
NM_001031696 |
| Protein Refseq : |
NP_001026866 |
| MIM : |
615698 |
| UniProt ID : |
Q8IV08 |
| Chromosome Location : |
19q13.2 |
| Pathway : |
Ether lipid metabolism; Glycerophospholipid biosynthesis; Phospholipid metabolism |
| Function : |
NAPE-specific phospholipase D activity; phospholipase D activity; protein binding |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
