"YY1" Related Products

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Recombinant Human YY1, His-tagged

Cat.No.: YY1-16H
Product Overview: Recombinant human YY1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Source: E.coli
Species: Human
Tag: His
Form: Liquid. In PBS,20% glycerol, 1mM DTT
Molecular Mass: 47.1kDa (437aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
Protein length: 1-414aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMASGDTL YIATDGSEMP AEIVELHEIE VETIPVETIE TTVVGEEEEE DDDDEDGGGG DHGGGGGHGH AGHHHHHHHH HHHPPMIALQ PLVTDDPTQV HHHQEVILVQ TREEVVGGDD SDGLRAEDGF EDQILIPVPA PAGGDDDYIE QTLVTVAAAG KSGGGGSSSS GGGRVKKGGG KKSGKKSYLS GGAGAAGGGG ADPGNKKWEQ KQVQIKTLEG EFSVTMWSSD EKKDIDHETV VEEQIIGENS PPDYSEYMTG KKLPPGGIPG IDLSDPKQLA EFARMKPRKI KEDDAPRTIA CPHKGCTKMF RDNSAMRKHL HTHGPRVHVC AECGKAFVES SKLKRHQLVH TGEKPFQCTF EGCGKRFSLD FNLRTHVRIH TGDRPYVCPF DGCNKKFAQS TNLKSHILTH AKAKNNQ
Purity: > 80% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml (determined by Bradford assay)
Gene Name: YY1 YY1 transcription factor [ Homo sapiens (human) ]
Official Symbol: YY1
Synonyms: YY1; DELTA; NF-E1; UCRBP; INO80S; YIN-YANG-1; YY1 transcription factor; transcriptional repressor protein YY1; YY-1; Yin and Yang 1 protein; INO80 complex subunit S; delta transcription factor
Gene ID: 7528
mRNA Refseq: NM_003403
Protein Refseq: NP_003394
MIM: 600013
UniProt ID: P25490
Chromosome Location: 14q
Pathway: Delta-Notch Signaling Pathway; E2F transcription factor network; Notch signaling pathway
Function: DNA binding; RNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription

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