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Active Recombinant Mouse Ifna2

Cat.No. : Ifna2-15M
Product Overview : Recombinant Mouse Ifna2 (amino acids Cys24-Glu190 of mature mouse IFN alpha2 accession # NM_010503) was expressed in E. coli.
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  • Gene Information
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Description : IFN-α2 is a type I interferon, previously known as B-cell interferon, leukocyte interferon, lymphoblast interferon, and pH2-stable interferon. IFN-α2 is one of at least 23 different known variants of IFN-α. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. IFN-α forms are produced by monocytes/macrophages, lymphoblastoid cells, fibroblasts, and a number of different cell types following induction by viruses, nucleic acids, glucocorticoid hormones, and low-molecular weight substances (n-butyrate, 5-bromodeoxyuridine). IFN-α2 demonstrates antiviral, antiparasitic, antiproliferative activities.
Source : E. coli
Species : Mouse
Form : Sterile liquid; 50mM NaAc, 0.1M NaCl, 0.5% BSA, pH 5.0.
Bio-activity : The recombinant mouse IFN alpha2 has been tested for inhibition of the cytopathic effect of EMC virus on L929 cells. The ED50 for this effect is typically 0.1 ng/mL, corresponding to a specific activity of 1 x 10e7 Units/mg.
Molecular Mass : The protein has a predicted molecular mass of 19,361. The non-reduced protein migrates as a 16 kDa polypeptide on SDS-PAGE. The DTT reduced protein migrates as an 18 kDa polypeptide.
Endotoxin : Less than 0.01 ng/ug cytokine as determined by the LAL assay.
Purity : > 98% as determined by SDS-PAGE
Applications : Cytokine Bioassays
Storage : Store at less than or equal to -70°C.
Gene Name : Ifna2 interferon alpha 2 [ Mus musculus (house mouse) ]
Official Symbol : Ifna2
Synonyms : Ifna2; Ifa2; interferon alpha 2; interferon alpha-2; IFN-alpha-2; interferon alpha family, gene 2
Gene ID : 15965
mRNA Refseq : NM_010503
Protein Refseq : NP_034633
UniProt ID : P01573
Chromosome Location : 4 C4; 4 42.02 cM
Pathway : Autoimmune thyroid disease; Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction
Function : cytokine activity; cytokine receptor binding; type I interferon receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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