Recombinant Human NELL1, His-tagged

• Cat.No.: NELL1-106H
• Product Overview: Recombinant Human Protein Kinase C-Binding Protein NELL1/NELL1 is produced in mammalian expression system in human cells. The target protein is expressed with sequence (Arg17-Asn810) of Human NELL1 fused with a 6His tag at the C-terminus.

Specification

• Description: This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 uM filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0.
• AA Sequence: RTVVGFGMDPDLQMDIVTELDLVNT TLGVAQVSGMHNASKAFLFQDIERE IHAAPHVSEKLIQLF QNKSEFTILATVQQKPSTSGVILSI RELEHSYFELESSGLRDEIRYHYIH NGKPRTEALPYRMAD GQWHKVALSVSASHLLLHVDCNRIY ERVIDPPDTNLPPGINLWLGQRNQK HGLFKGIIQDGKIIF MPNGYITQCPNLNHTCPTCSDFLSL VQGIMDLQELLAKMTAKLNYAETRL SQLENCHCEKTCQVS GLLYRDQDSWVDGDHCRNCTCKSGA VECRRMSCPPLNCSPDSLPVHIAGQ CCKVCRPKCIYGGKV LAEGQRILTKSCRECRGGVLVKITE MCPPLNCSEKDHILPENQCCRVCRG HNFCAEGPKCGENSE CKNWNTKATCECKSGYISVQGDSAY CEDIDECAAKMHYCHANTVCVNLPG LYRCDCVPGYIRVDD FSCTEHDECGSGQHNCDENAICTNT VQGHSCTCKPGYVGNGTICRAFCEE GCRYGGTCVAPNKCV CPSGFTGSHCEKDIDECSEGIIECH NHSRCVNLPGWYHCECRSGFHDDGT YSLSGESCIDIDECA LRTHTCWNDSACINLAGGFDCLCPS GPSCSGDCPHEGGLKHNGQVWTLKE DRCSVCSCKDGKIFC RRTACDCQNPSADLFCCPECDTRVT SQCLDQNGHKLYRSGDNWTHSCQQC RCLEGEVDCWPLTCP NLSCEYTAILEGECCPRCVSDPCLA DNITYDIRKTCLDSYGVSRLSGSVW TMAGSPCTTCKCKNG RVCCSVDFECLQNNLDHHHHHH
• Endotoxin: Less than 0.1 ng/µg (1 IEU/µg).
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Gene Information

• Gene Name: NELL1 NEL-like 1 (chicken) [ Homo sapiens (human) ]
• Official Symbol: NELL1
• Synonyms: NELL1; NRP1; IDH3GL; NEL-like 1 (chicken); protein kinase C-binding protein NELL1; nel-related protein 1; neural epidermal growth factor-like 1
• Gene ID: 4745
• mRNA Refseq: NM_006157
• Protein Refseq: NP_006148
• MIM: 602319
• UniProt ID: Q92832
• Chromosome Location: 11p15.1
• Function: calcium ion binding; protein binding