Recombinant Human kallikrein-related peptidase 2, His-tagged
Cat.No. : | KLK2-221H |
Product Overview : | KLK2, 25-261aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | KLK2 is a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. KLK2 is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. Recombinant human KLK2 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
Molecular Mass : | 28.5kDa (260aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSIVGGWEC EKHSQPWQVA VYSHGWAHCG GVLVHPQWVL TAAHCLKKNS QVWLGRHNLF EPEDTGQRVP VSHSFPHPLY NMSLLKHQSL RPDEDSSHDL MLLRLSEPAK ITDVVKVLGL PTQEPALGTT CYASGWGSIE PEEFLRPRSL QCVSLHLLSN DMCARAYSEK VTEFMLCAGL WTGGKDTCGG DSGGPLVCNG VLQGITSWGP EPCALPEKPA VYTKVVHYRK WIKDTIAANP |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | KLK2 kallikrein-related peptidase 2 [ Homo sapiens ] |
Official Symbol : | KLK2 |
Synonyms : | KLK2; kallikrein-related peptidase 2; kallikrein 2, prostatic; kallikrein-2; tissue kallikrein-2; glandular kallikrein 2; glandular kallikrein-1; hK2; hGK-1; KLK2A2; FLJ17010; FLJ17011; MGC12201; |
Gene ID : | 3817 |
mRNA Refseq : | NM_001002231 |
Protein Refseq : | NP_001002231 |
MIM : | 147960 |
UniProt ID : | P20151 |
Chromosome Location : | 19q13.33 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; Extracellular matrix organization, organism-specific biosystem; Regulation of Androgen receptor activity, organism-specific biosystem; |
Function : | peptidase activity; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
KLK2-1257H | Recombinant Human KLK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
KLK2-2372H | Recombinant Human KLK2 Protein, His-tagged | +Inquiry |
KLK2-2373H | Recombinant Human KLK2 Protein, His-tagged | +Inquiry |
KLK2-2371H | Recombinant Human KLK2 Protein, His-tagged | +Inquiry |
KLK2-153H | Recombinant Human KLK2 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
KLK2-947HCL | Recombinant Human KLK2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket