"PNRC2" Related Products

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Recombinant Human proline-rich nuclear receptor coactivator 2, His-tagged

Cat.No.: PNRC2-231H
Product Overview: PNRC2, 1-139aa, Human, His tag, E.coli
Description: PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. This protein may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. It is required for UPF1/RENT1 localization to the P-body and also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure. Recombinant human PNCR2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
Molecular Mass: 18.0kDa (162aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGGGERY NIPAPQSRNV SKNQQQLNRQ KTKEQNSQMK IVHKKKERGH GYNSSAAAWQ AMQNGGKNKN FPNNQSWNSS LSGPRLLFKS QANQNYAGAK FSEPPSPSVL PKPPSHWVPV SFNPSDKEIM TFQLKTLLKV QV
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: PNRC2 proline-rich nuclear receptor coactivator 2 [ Homo sapiens ]
Official Symbol: PNRC2
Synonyms: PNRC2; proline-rich nuclear receptor coactivator 2; FLJ20312; MGC99541;
Gene ID: 55629
mRNA Refseq: NM_017761
Protein Refseq: NP_060231
MIM: 611882
UniProt ID: Q9NPJ4
Chromosome Location: 1p36.11
Function: protein binding;

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