Recombinant Human mesenchyme homeobox 2, His-tagged

• Cat.No.: MEOX2-240H
• Product Overview: MEOX2, 188-304aa, Human, His tag, E.coli

Specification

• Description: Homeobox protein MOX-2, also known as MEOX2, belongs to a family of nonclustered, diverged homeobox genes that are expressed in overlapping patterns in the paraxial mesoderm and its derivatives. It may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse MEOX2 may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer"s disease. Recombinant human MEOX2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT
• Molecular Mass: 15.9 kDa (140aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSRKERTAF TKEQIRELEA EFAHHNYLTR LRRYEIAVNL DLTERQVKVW FQNRRMKWKR VKGGQQGAAA REKELVNVKK GTLLPSELSG IGAATLQQTG DSIANEDSHD SDHSSEHAHL
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MEOX2 mesenchyme homeobox 2 [ Homo sapiens ]
• Official Symbol: MEOX2
• Synonyms: MEOX2; mesenchyme homeobox 2; GAX, mesenchyme homeo box 2 (growth arrest specific homeo box) , mesenchyme homeobox 2 (growth arrest specific homeo box); homeobox protein MOX-2; growth arrest specific homeobox; MOX2; growth arrest-specific homeobox; growth arrest-specific homeo box; mesenchyme homeo box 2 (growth arrest-specific homeo box); GAX
• Gene ID: 4223
• mRNA Refseq: NM_005924
• Protein Refseq: NP_005915
• MIM: 600535
• UniProt ID: P50222
• Chromosome Location: 7p22.1-p21.3
• Function: protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity