Recombinant Human Sjogren syndrome/scleroderma autoantigen 1, His-tagged

• Cat.No.: SSSCA1-313H
• Product Overview: SSSCA1, 1-199aa, Human, His tag, E.coli

Specification

• Description: SSSCA1 is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren"s syndrome. Subcellular localization has not yet been established. Recombinant human SSSCA1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 23.9kDa (222aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMALNGAE VDDFSWEPPT EAETKVLQAR RERQDRISRL MGDYLLRGYR MLGETCADCG TILLQDKQRK IYCVACQELD SDVDKDNPAL NAQAALSQAR EHQLASASEL PLGSRPAPQP PVPRPEHCEG AAAGLKAAQG PPAPAVPPNT DVMACTQTAL LQKLTWASAE LGSSTSLETS IQLCGLIRAC AEALRSLQQL QH
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 [ Homo sapiens ]
• Official Symbol: SSSCA1
• Synonyms: SSSCA1; Sjogren syndrome/scleroderma autoantigen 1; Sjogrens syndrome/scleroderma autoantigen 1; Sjoegren syndrome/scleroderma autoantigen 1; p27; autoantigen p27; centromeric autoantigen (27kD)
• Gene ID: 10534
• mRNA Refseq: NM_006396
• Protein Refseq: NP_006387
• MIM: 606044
• UniProt ID: O60232
• Chromosome Location: 11q13.1
• Function: identical protein binding