"EDA2R" Related Products

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Recombinant Human ectodysplasin A2 receptor, His-tagged

Cat.No.: EDA2R-314H
Product Overview: EDA2R, 1-138aa, Human, His tag, E.coli
Description: EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. EDA2R specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. Recombinant human EDA2R protein , fused to His-tag at N-terminus, was expressed in E.coli.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
Molecular Mass: 17.7 kDa (161aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA T
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 1mg/ml (determined by Bradford assay)
Gene Name: EDA2R ectodysplasin A2 receptor [ Homo sapiens ]
Official Symbol: EDA2R
Synonyms: EDA2R; ectodysplasin A2 receptor; tumor necrosis factor receptor superfamily member 27; EDA A2R; EDAA2R; TNFRSF27; XEDAR; EDA-A2 receptor; X-linked ectodysplasin-A2 receptor; tumor necrosis factor receptor superfamily member XEDAR; EDA-A2R;
Gene ID: 60401
mRNA Refseq: NM_001199687
Protein Refseq: NP_001186616
MIM: 300276
UniProt ID: Q9HAV5
Chromosome Location: Xq11.1
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function: protein binding; receptor activity; tumor necrosis factor-activated receptor activity;

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