Recombinant Human ectodysplasin A2 receptor, His-tagged
Cat.No. : | EDA2R-314H |
Product Overview : | EDA2R, 1-138aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. EDA2R specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. Recombinant human EDA2R protein , fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea |
Molecular Mass : | 17.7 kDa (161aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA T |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Bradford assay) |
Gene Name : | EDA2R ectodysplasin A2 receptor [ Homo sapiens ] |
Official Symbol : | EDA2R |
Synonyms : | EDA2R; ectodysplasin A2 receptor; tumor necrosis factor receptor superfamily member 27; EDA A2R; EDAA2R; TNFRSF27; XEDAR; EDA-A2 receptor; X-linked ectodysplasin-A2 receptor; tumor necrosis factor receptor superfamily member XEDAR; EDA-A2R; |
Gene ID : | 60401 |
mRNA Refseq : | NM_001199687 |
Protein Refseq : | NP_001186616 |
MIM : | 300276 |
UniProt ID : | Q9HAV5 |
Chromosome Location : | Xq11.1 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | protein binding; receptor activity; tumor necrosis factor-activated receptor activity; |
Products Types
◆ Recombinant Protein | ||
EDA2R-4393H | Recombinant Human EDA2R Protein, His (Fc)-Avi-tagged | +Inquiry |
EDA2R-1287C | Recombinant Cynomolgus EDA2R protein(Met1-Glu136), hFc-tagged | +Inquiry |
Eda2r-7460R | Recombinant Rat Eda2r protein(Met2-Glu137), hFc-tagged | +Inquiry |
Eda2r-7461R | Recombinant Rat Eda2r protein(Met2-Glu137), His-tagged | +Inquiry |
EDA2R-3045H | Recombinant Human EDA2R Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
EDA2R-1335MCL | Recombinant Mouse EDA2R cell lysate | +Inquiry |
EDA2R-2021HCL | Recombinant Human EDA2R cell lysate | +Inquiry |
EDA2R-990CCL | Recombinant Cynomolgus EDA2R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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