"UGT8" Related Products

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Recombinant Human UDP glycosyltransferase 8, His-tagged

Cat.No.: UGT8-331H
Product Overview: UGT8, 21-541aa, Human, His tag, E.coli
Description: UDP glycosyltransferase 8, also known as UGT8, catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Recombinant human UGT8 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
Molecular Mass: 61.6 kDa (544aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSAKIIIVP PIMFESHMYI FKTLASALHE RGHHTVFLLS EGRDIAPSNH YSLQRYPGIF NSTTSDAFLQ SKMRNIFSGR LTAIELFDIL DHYTKNCDLM VGNHALIQGL KKEKFDLLLV DPNDMCGFVI AHLLGVKYAV FSTGLWYPAE VGAPAPLAYV PEFNSLLTDR MNLLQRMKNT GVYLISRLGV SFLVLPKYER IMQKYNLLPE KSMYDLVHGS SLWMLCTDVA LEFPRPTLPN VVYVGGILTK PASPLPEDLQ RWVNGANEHG FVLVSFGAGV KYLSEDIANK LAGALGRLPQ KVIWRFSGPK PKNLGNNTKL IEWLPQNDLL GHSKIKAFLS HGGLNSIFET MYHGVPVVGI PLFGDHYDTM TRVQAKGMGI LLEWKTVTEK ELYEALVKVI NNPSYRQRAQ KLSEIHKDQP GHPVNRTIYW IDYIIRHNGA HHLRAAVHQI SFCQYFLLDI AFVLLLGAAL LYFLLSWVTK FIYRKIKSLW SRNKHSTVNG HYHNGILNGK YKRNGHIKHE KKVK
Purity: >85% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 1mg/ml (determined by Bradford assay)
Gene Name: UGT8?UDP glycosyltransferase 8 [?Homo sapiens?(human) ]
Official Symbol: UGT8
Synonyms: UGT8; CGT; UGT4; UDP glycosyltransferase 8; 2-hydroxyacylsphingosine; 1-beta-galactosyltransferase; cerebroside synthase; ceramide UDP-galactosyltransferase; uridine diphosphate glycosyltransferase 8; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase; NP_001121646.1; EC 2.4.1.45; NP_003351.2
Gene ID: 7368
mRNA Refseq: NM_001128174
Protein Refseq: NP_001121646
MIM: 601291
UniProt ID: Q16880
Chromosome Location: 4q26
Pathway: Cerebroside and sulfatide biosynthesis; Sphingolipid metabolism
Function: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity; UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity

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