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Recombinant Human X-ray repair complementing defective repair in Chinese hamster cells 2, His-tagged

Cat.No. : XRCC2-412H
Product Overview : XRCC2,1-280aa, Human, His tag, E.coli
  • Specification
  • Gene Information
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Description : XRCC2 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. Recombinant human XRCC2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Molecular Mass : 34.3 kDa (303aa)
AA Sequence : HHHHH SSGLVPRGSH MGSMCSAFHR AESGTELLAR LEGRSSLKEI EPNLFADEDS PVHGDILEFH GPEGTGKTEM LYHLTARCIL PKSEGGLEVE VLFIDTDYHF DMLRLVTILE HRLSQSSEEI IKYCLGRFFL VYCSSSTHLL LTLYSLESMF CSHPSLCLLI LDSLSAFYWI DRVNGGESVN LQESTLRKCS QCLEKLVNDY RLVLFATTQT IMQKASSSSE EPSHASRRLC DVDIDYRPYL CKAWQQLVKH RMFFSKQDDS QSSNQFSLVS RCLKSNSLKK HFFIIGESGV EFC
Purity : >80% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 [ Homo sapiens ]
Official Symbol : XRCC2
Synonyms : XRCC2; X-ray repair complementing defective repair in Chinese hamster cells 2; DNA repair protein XRCC2; RAD51 like; X-ray repair cross-complementing protein 2; X-ray repair, complementing defective, repair in Chinese hamster; DKFZp781P0919;
Gene ID : 7516
mRNA Refseq : NM_005431
Protein Refseq : NP_005422
MIM : 600375
UniProt ID : O43543
Chromosome Location : 7q36
Pathway : Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
Function : ATP binding; DNA binding; DNA-dependent ATPase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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