Recombinant Human retinaldehyde binding protein 1, His-tagged

• Cat.No.: RLBP1-425H
• Product Overview: RLBP1, 1-317aa, Human, His tag, E.coli

Specification

• Description: RLBP1 is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens. Recombinant human RLBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
• Molecular Mass: 38.9kDa (340aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEGVGT FRMVPEEEQE LRAQLEQLTT KDHGPVFGPC SQLPRHTLQK AKDELNEREE TREEAVRELQ EMVQAQAASG EELAVAVAER VQEKDSGFFL RFIRARKFNV GRAYELLRGY VNFRLQYPEL FDSLSPEAVR CTIEAGYPGV LSSRDKYGRV VMLFNIENWQ SQEITFDEIL QAYCFILEKL LENEETQING FCIIENFKGF TMQQAASLRT SDLRKMVDML QDSFPARFKA IHFIHQPWYF TTTYNVVKPF LKSKLLERVF VHGDDLSGFY QEIDENILPS DFGGTLPKYD GKAVAEQLFG PQAQAENTAF
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RLBP1 retinaldehyde binding protein 1 [ Homo sapiens ]
• Official Symbol: RLBP1
• Synonyms: RLBP1; retinaldehyde binding protein 1; retinaldehyde-binding protein 1; CRALBP; cellular retinaldehyde-binding protein; cellular retinaldehyde-binding protein-1; MGC3663
• Gene ID: 6017
• mRNA Refseq: NM_000326
• Protein Refseq: NP_000317
• MIM: 180090
• UniProt ID: P12271
• Chromosome Location: 15q26.1
• Pathway: Vitamin A and carotenoid metabolism, organism-specific biosystem; the visual cycle, conserved biosystem; the visual cycle, organism-specific biosystem
• Function: 11-cis retinal binding; binding; retinol binding; transporter activity