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Recombinant Human proline-rich transmembrane protein 2, His-tagged

Cat.No. : PRRT2-434H
Product Overview : PRRT2, 1-268aa, Human, His tag, E.coli
  • Specification
  • Gene Information
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Description : PRRT2 is a transmembrane protein containing a proline-rich domain in its N-terminal half. Studies in mice suggest that it is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. Mutations in this gene are associated with paroxysmal kinesigenic dyskinesia. Almost one third of sporadic PKC patients also carry PRRT2 mutations. Recombinant human PRRT2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT.
Molecular Mass : 29.7 kDa (291aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMAASSSE ISEMKGVEES PKVPGEGPGH SEAETGPPQV LAGVPDQPEA PQPGPNTTAA PVDSGPKAGL APETTETPAG ASETAQATDL SLSPGGESKA NCSPEDPCQE TVSKPEVSKE ATADQGSRLE SAAPPEPAPE PAPQPDPRPD SQPTPKPALQ PELPTQEDPT PEILSESVGE KQENGAVVPL QAGDGEEGPA PEPHSPPSKK SPPANGAPPR VLQQLVEEDR MRRAHSGHPG SPRGSLSRHP SSQLAGPGVE GGEGTQKPRD Y
Purity : >85% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name : PRRT2 proline-rich transmembrane protein 2 [ Homo sapiens ]
Official Symbol : PRRT2
Synonyms : PRRT2; proline-rich transmembrane protein 2; DKFZp547J199; FLJ25513; IFITMD1; interferon induced transmembrane protein domain containing 1; PKC; EKD1; DYT10;
Gene ID : 112476
mRNA Refseq : NM_001256442
Protein Refseq : NP_001243371
MIM : 614386
UniProt ID : Q7Z6L0
Chromosome Location : 16p11.2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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