Recombinant Human matrix metallopeptidase 10 (stromelysin 2), His-tagged
Cat.No. : | MMP10-440H |
Product Overview : | MMP10, 99-476aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | MMP10 protein of the matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP"s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. MMP10 is part of a cluster of MMP genes which localize to chromosome 11q22.3. Recombinant human MMP10 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol |
Molecular Mass : | 45.4kDa (401aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSFSSFPGM PKWRKTHLTY RIVNYTPDLP RDAVDSAIEK ALKVWEEVTP LTFSRLYEGE ADIMISFAVK EHGDFYSFDG PGHSLAHAYP PGPGLYGDIH FDDDEKWTED ASGTNLFLVA AHELGHSLGL FHSANTEALM YPLYNSFTEL AQFRLSQDDV NGIQSLYGPP PASTEEPLVP TKSVPSGSEM PAKCDPALSF DAISTLRGEY LFFKDRYFWR RSHWNPEPEF HLISAFWPSL PSYLDAAYEV NSRDTVFIFK GNEFWAIRGN EVQAGYPRGI HTLGFPPTIR KIDAAVSDKE KKKTYFFAAD KYWRFDENSQ SMEQGFPRLI ADDFPGVEPK VDAVLQAFGF FYFFSGSSQF EFDPNARMVT HILKSNSWLH C |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | MMP10 matrix metallopeptidase 10 (stromelysin 2) [ Homo sapiens ] |
Official Symbol : | MMP10 |
Synonyms : | MMP10; matrix metallopeptidase 10 (stromelysin 2); matrix metalloproteinase 10 (stromelysin 2) , STMY2; stromelysin-2; MMP-10; transin 2; transin-2; stromelysin 2; matrix metalloprotease 10; matrix metalloproteinase-10; matrix metalloproteinase 10 (stromelysin 2); SL-2; STMY2; |
Gene ID : | 4319 |
mRNA Refseq : | NM_002425 |
Protein Refseq : | NP_002416 |
MIM : | 185260 |
UniProt ID : | P09238 |
Chromosome Location : | 11q22.3 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem; |
Function : | calcium ion binding; metalloendopeptidase activity; peptidase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
MMP10-3366R | Recombinant Rat MMP10 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP10-5415H | Recombinant Human MMP10 Protein, GST-tagged | +Inquiry |
MMP10-1457H | Recombinant Human MMP10 Protein (99-476 aa), His-tagged | +Inquiry |
MMP10-1118R | Recombinant Rabbit MMP10 Protein, His-tagged | +Inquiry |
MMP10-5041H | Recombinant Human MMP10, His-tagged | +Inquiry |
◆ Lysates | ||
MMP10-4282HCL | Recombinant Human MMP10 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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