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Recombinant Human interferon, lambda 2, His-tagged

Cat.No.: IFNL2-466H
Product Overview: IFNL2, 26-200aa Human, His tag, E.coli
Description: IFNL2, also known as Interleukin 28A (IL28A), is a cytokine distantly related to type I interferons and the IL-10 family. Interleukin 28A (IL28A), Interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). Recombinant human IFNL2 protein, fused to His-tag at N-terminus, was expressed in E.coli .
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Molecular Mass: 22.1 kDa (198aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSVPVARLH GALPDARGCH IAQFKSLSPQ ELQAFKRAKD ALEESLLLKD CRCHSRLFPR TWDLRQLQVR ERPMALEAEL ALTLKVLEAT ADTDPALVDV LDQPLHTLHH ILSQFRACIQ PQPTAGPRTR GRLHHWLYRL QEAPKKESPG CLEASVTFNL FRLLTRDLNC VASGDLCV
Purity: >85 % by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: IFNL2?interferon, lambda 2 [?Homo sapiens?(human) ]
Official Symbol: IFNL2
Synonyms: IFNL2; IL28A; IL-28A; interferon, lambda 2; interferon lambda-2; IFN-lambda-2; interleukin-28A; cytokine Zcyto20; interferon lambda 2; interferon-lambda 2; interleukin 28A (interferon, lambda 2)
Gene ID: 282616
mRNA Refseq: NM_172138
Protein Refseq: NP_742150
MIM: 607401
UniProt ID: Q8IZJ0
Chromosome Location: 19q13.13
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Type III interferon signaling
Function: cytokine activity

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