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Recombinant Human interferon, lambda 2, His-tagged

Cat.No. : IFNL2-466H
Product Overview : IFNL2, 26-200aa Human, His tag, E.coli
  • Specification
  • Gene Information
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Description : IFNL2, also known as Interleukin 28A (IL28A), is a cytokine distantly related to type I interferons and the IL-10 family. Interleukin 28A (IL28A), Interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). Recombinant human IFNL2 protein, fused to His-tag at N-terminus, was expressed in E.coli .
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Molecular Mass : 22.1 kDa (198aa)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSVPVARLH GALPDARGCH IAQFKSLSPQ ELQAFKRAKD ALEESLLLKD CRCHSRLFPR TWDLRQLQVR ERPMALEAEL ALTLKVLEAT ADTDPALVDV LDQPLHTLHH ILSQFRACIQ PQPTAGPRTR GRLHHWLYRL QEAPKKESPG CLEASVTFNL FRLLTRDLNC VASGDLCV
Purity : >85 % by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : IFNL2?interferon, lambda 2 [?Homo sapiens?(human) ]
Official Symbol : IFNL2
Synonyms : IFNL2; IL28A; IL-28A; interferon, lambda 2; interferon lambda-2; IFN-lambda-2; interleukin-28A; cytokine Zcyto20; interferon lambda 2; interferon-lambda 2; interleukin 28A (interferon, lambda 2)
Gene ID : 282616
mRNA Refseq : NM_172138
Protein Refseq : NP_742150
MIM : 607401
UniProt ID : Q8IZJ0
Chromosome Location : 19q13.13
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Type III interferon signaling
Function : cytokine activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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