"IRF5" Related Products

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Recombinant Human interferon regulatory factor 5, His-tagged

Cat.No.: IRF5-520H
Product Overview: IRF5, 176-240aa Human, His tag, E.coli
Description: IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Molecular Mass: 10.7 kDa (101aa) confirmed by MALDI-TOF
AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I
Purity: >85 % by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml (determined by Bradford assay)
Gene Name: IRF5 interferon regulatory factor 5 [ Homo sapiens ]
Official Symbol: IRF5
Synonyms: IRF5; interferon regulatory factor 5; IRF-5; SLEB10;
Gene ID: 3663
mRNA Refseq: NM_001098627
Protein Refseq: NP_001092097
MIM: 607218
UniProt ID: Q13568
Chromosome Location: 7q32
Pathway: Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon alpha/beta signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem;
Function: protein binding; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity;

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