Recombinant Human suppressor of IKBKE 1, His-tagged
Cat.No. : | SIKE1-521H |
Product Overview : | SIKE1, 1-207aa Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | SIKE interacts with IKK-epsilon and TBK1 and acts as a suppressor of TLR3 and virus-triggered interferon activation pathways. Recombinant human SIKE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT |
Molecular Mass : | 26.1 kDa (230aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMSCTIEK ILTDAKTLLE RLREHDAAAE SLVDQSAALH RRVAAMREAG TALPDQYQED ASDMKDMSKY KPHILLSQEN TQIRDLQQEN RELWISLEEH QDALELIMSK YRKQMLQLMV AKKAVDAEPV LKAHQSHSAE IESQIDRICE MGEVMRKAVQ VDDDQFCKIQ EKLAQLELEN KELRELLSIS SESLQARKEN SMDTASQAIK |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Gene Name : | SIKE1 suppressor of IKBKE 1 [ Homo sapiens ] |
Official Symbol : | SIKE1 |
Synonyms : | SIKE; RP5-1000E10.4 |
Gene ID : | 80143 |
mRNA Refseq : | NM_025073.2 |
Protein Refseq : | NP_079349.2 |
MIM : | 611656 |
UniProt ID : | Q9BRV8 |
Chromosome Location : | 1p13.2 |
Pathway : | Immune System, organism-specific biosystem;Innate Immune System, organism-specific biosystem;RIG-I-like receptor signaling pathway, organism-specific biosystem;RIG-I-like receptor signaling pathway, conserved biosystem;RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways, organism-specific biosystem;TRAF3-dependent IRF activation pathway, organism-specific biosystem;TRAF6 mediated IRF7 activation, organism-specific biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
SIKE1-5062R | Recombinant Rat SIKE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIKE1-4020R | Recombinant Rhesus Macaque SIKE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Sike1-5879M | Recombinant Mouse Sike1 Protein, Myc/DDK-tagged | +Inquiry |
SIKE1-8173M | Recombinant Mouse SIKE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIKE1-30168H | Recombinant Human SIKE1 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
SIKE1-1840HCL | Recombinant Human SIKE1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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