Recombinant Human gremlin 2, DAN family BMP antagonist, His-tagged
Cat.No. : | GREM2-534H |
Product Overview : | GREM2, 22-168aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | GREM2 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this protein belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this protein may play a role in regulating organogenesis, body patterning, and tissue differentiation. Recombinant human GREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
Molecular Mass : | 19 kDa (170aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSRKNRPAG AIPSPYKDGS SNNSERWQHQ IKEVLASSQE ALVVTERKYL KSDWCKTQPL RQTVSEEGCR SRTILNRFCY GQCNSFYIPR HVKKEEESFQ SCAFCKPQRV TSVLVELECP GLDPPFRLKK IQKVKQCRCM SVNLSDSDKQ |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | GREM2 gremlin 2 [ Homo sapiens ] |
Official Symbol : | GREM2 |
Synonyms : | GREM2; gremlin 2; gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis); gremlin-2; CKTSF1B2; DAND3; FLJ21195; Prdc; protein related to DAN and cerberus; DAN domain family member 3; cysteine knot superfamily 1, BMP antagonist 2; gremlin 2, cysteine knot superfamily, homolog; PRDC; |
Gene ID : | 64388 |
mRNA Refseq : | NM_022469 |
Protein Refseq : | NP_071914 |
MIM : | 608832 |
UniProt ID : | Q9H772 |
Chromosome Location : | 1q43 |
Pathway : | Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; |
Function : | cytokine activity; |
Products Types
◆ Recombinant Protein | ||
GREM2-3919M | Recombinant Mouse GREM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
GREM2-1793R | Recombinant Rhesus Macaque GREM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
GREM2-5324H | Recombinant Human GREM2 Protein, GST-tagged | +Inquiry |
GREM2-2462Z | Recombinant Zebrafish GREM2 | +Inquiry |
GREM2-1972R | Recombinant Rhesus monkey GREM2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GREM2-5752HCL | Recombinant Human GREM2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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