Recombinant Human valosin containing protein lysine (K) methyltransferase, His-tagged

• Cat.No.: VCPKMT-680H
• Product Overview: VCPKMT, 1-229aa Human, His tag, E.coli

Specification

• Description: VCPKMT is a protein-lysine N-methyltransferase that specifically trimethylates "Lys-315" of VCP/p97; this modification may decrease VCP ATPase activity. Recombinant human VCPKMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Phosphate buffer saline (pH 8.0) containing 10% glycerol, 1mM DTT
• Molecular Mass: 28.2 kDa (252aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMADTLES SLEDPLRSFV RVLEKRDGTV LRLQQYSSGG VGCVVWDAAI VLSKYLETPE FSGDGAHALS RRSVLELGSG TGAVGLMAAT LGADVVVTDL EELQDLLKMN INMNKHLVTG SVQAKVLKWG EEIEGFPSPP DFILMADCIY YEESLEPLLK TLKDISGFET CIICCYEQRT MGKNPEIEKK YFELLQLDFD FEKIPLEKHD EEYRSEDIHI IYIRKKKSKF PS
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: VCPKMT valosin containing protein lysine (K) methyltransferase [ Homo sapiens (human) ]
• Official Symbol: VCPKMT
• Synonyms: VCPKMT; VCP-KMT; METTL21D; C14orf138; valosin containing protein lysine (K) methyltransferase; protein-lysine; methyltransferase METTL21D; methyltransferase like 21D; VCP lysine methyltransferase; methyltransferase-like protein 21D; valosin-containing protein lysine methyltransferase
• Gene ID: 79609
• mRNA Refseq: NM_001040662
• Protein Refseq: NP_001035752
• MIM: 615260
• UniProt ID: Q9H867
• Chromosome Location: 14q21.3
• Function: protein binding; protein-lysine N-methyltransferase activity