Recombinant Human RAB3A interacting protein (rabin3)-like 1, His-tagged

• Cat.No.: RAB3IL1-685H
• Product Overview: RAB3IL, 1-382aa, Human, His tag, E.col

Specification

• Description: Guanine nucleotide exchange factor for Rab-3A isoform 1, also known as RAB3IL, is a 382 amino acid protein that belongs to the SEC2 family. RAB3IL1 is a guanine nucleotide exchange factor (GEF) for Rab3A. RAB3IL1 competes for an interaction with Rab3A and IHPK1 through its coiled coil domain, which does not require IHPK1 kinase activity. Recombinant human RAB3IL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In Phosphate buffer saline (pH 7.4) containing 50% glycerol
• Molecular Mass: 45kDa (405aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMWSGPPQ PDQGLPPPLA AVPVPWKSTD PCQGHRESPG ALVETSAGEE AQGQEGPAAA QLDVLRLRSS SMEIREKGSE FLKEELHRAQ KELKLKDEEC ERLSKVREQL EQELEELTAS LFEEAHKMVR EANMKQAASE KQLKEARGKI DMLQAEVTAL KTLVITSTPA SPNRELHPQL LSPTKAGPRK GHSRHKSTSS TLCPAVCPAA GHTLTPDREG KEVDTILFAE FQAWRESPTL DKTCPFLERV YREDVGPCLD FTMQELSVLV RAAVEDNTLT IEPVASQTLP TVKVAEVDCS STNTCALSGL TRTCRHRIRL GDSKSHYYIS PSSRARITAV CNFFTYIRYI QQGLVRQDAE PMFWEIMRLR KEMSLAKLGF FPQEA
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RAB3IL1 RAB3A interacting protein (rabin3)-like 1 [ Homo sapiens ]
• Official Symbol: RAB3IL1
• Synonyms: RAB3IL1; RAB3A interacting protein (rabin3)-like 1; guanine nucleotide exchange factor for Rab-3A; rabin3-like 1; rab3A-interacting-like protein 1; rab-3A-interacting-like protein 1; guanine nucleotide exchange factor for Rab3A; GRAB
• Gene ID: 5866
• mRNA Refseq: NM_013401
• Protein Refseq: NP_037533
• UniProt ID: Q8TBN0
• Chromosome Location: 11q12.2
• Function: Rab guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; kinase binding; protein binding