"AKR1C4" Related Products

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Recombinant Human AKR1C4, His-tagged

Cat.No.: AKR1C4-218H
Product Overview: A DNA sequence encoding the human AKR1C4 (AAH20744.1) (Met1-Tyr323) was expressed with a polyhistidine tag at the N-terminus.
Source: E. coli
Species: Human
Tag: His
Form: Lyophilized from sterile PBS, pH7.4.
Molecular Mass: The recombinant human AKR1C4 consists of 341 amino acids and predicts a molecular mass of 39.4 KDa. It migrates as an approximately 35-40 KDa band in SDS-PAGE under reducing conditions.
Protein length: Met1-Tyr323
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: >85 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name: AKR1C4 aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) [ Homo sapiens ]
Official Symbol: AKR1C4
Synonyms: AKR1C4; aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4); CHDR; aldo-keto reductase family 1 member C4; 3 alpha HSD; C11; CDR; DD4; HAKRA; MGC22581; 3-alpha-HSD1; dihydrodiol dehydrogenase isozyme DD4; type I 3-alpha-hydroxysteroid dehydrogenase; DD-4; 3-alpha-HSD;
Gene ID: 1109
mRNA Refseq: NM_001818
Protein Refseq: NP_001809
MIM: 600451
UniProt ID: P17516
Chromosome Location: 10p15.1
Pathway: Bile acid and bile salt metabolism, organism-specific biosystem; Bile acid biosynthesis, cholesterol =>cholate, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function: aldo-keto reductase (NADP) activity; androsterone dehydrogenase (B-specific) activity; androsterone dehydrogenase activity; bile acid transmembrane transporter activity; chlordecone reductase activity; electron carrier activity; oxidoreductase activity; o

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