Recombinant Human KIRREL, Fc-tagged

• Cat.No.: KIRREL-323H
• Product Overview: A DNA sequence encoding the human KIRREL (NP_060710.3) (Met1-Leu493) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Source: Human Cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human KIRREL/Fc comprises 715 amino acids and has a predicted molecular mass of 78.8 kDa. The apparent molecular mass of the protein is approximately 96.1 kDa in SDS-PAGE under reducing conditions.
• Protein length: Met1-Leu493
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: KIRREL kin of IRRE like (Drosophila) [ Homo sapiens ]
• Official Symbol: KIRREL
• Synonyms: KIRREL; kin of IRRE like (Drosophila); kin of IRRE-like protein 1; NEPH1; nephrin like protein 1; nephrin related; nephrin-like protein 1; kin of irregular chiasm-like protein 1; FLJ10845; MGC129542; MGC129543
• Gene ID: 55243
• mRNA Refseq: NM_018240
• Protein Refseq: NP_060710
• MIM: 607428
• UniProt ID: Q96J84
• Chromosome Location: 1q21-q25
• Pathway: Cell-Cell communication, organism-specific biosystem; Nephrin interactions, organism-specific biosystem; Nephrin/Neph1 signaling in the kidney podocyte, organism-specific biosystem