"Fgf23" Related Products

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Recombinant Mouse Fgf23

Cat.No.: Fgf23-27M
Product Overview: Recombinant murine FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues.
Description: This gene encodes a member of the fibroblast growth factor family. The encoded protein regulates phosphate homeostasis and vitamin D metabolism. Mutation of the related gene in humans causes autosomal dominant hypophosphatemic rickets (ADHR). The secreted protein is further cleaved into N- and C-terminal chains, which results in loss of function.
Source: E. coli
Species: Mouse
Bio-activity: Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells. The expected ED50 for this effect is 0.3-0.5 μg/ml, in the presence of murine Klotho and heparin.
Molecular Mass: 25.5 kDa
AA Sequence: MYPDTSPLLG SNWGSLTHLY TATARTSYHL QIHRDGHVDG TPHQTIYSAL MITSEDAGSV VITGAMTRRF LCMDLHGNIF GSLHFSPENC KFRQWTLENG YDVYLSQKHH YLVSLGRAKR IFQPGTNPPP FSQFLARRNE VPLLHFYTVR PRRHTRSAED PPERDPLNVL KPRPRATPVP VSCSRELPSA EEGGPAASDP LGVLRRGRGD ARGGAGGADR CRPFPRFV
Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.
Gene Name: Fgf23 fibroblast growth factor 23 [ Mus musculus (house mouse) ]
Official Symbol: Fgf23
Synonyms: Fgf23; fibroblast growth factor 23; fibroblast growth factor 23; FGF-23
Gene ID: 64654
mRNA Refseq: NM_022657
Protein Refseq: NP_073148
UniProt ID: Q9EPC2
Chromosome Location: 6 F3; 6
Pathway: Activated point mutants of FGFR2; DAP12 interactions; Downstream signal transduction
Function: fibroblast growth factor receptor binding; growth factor activity; protein binding

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