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Recombinant Mouse Actg1, His-tagged

Cat.No. : Actg1-3094M
Product Overview : Actin, cytoplasmic 2 (Actg1)
  • Specification
  • Gene Information
  • Related Products
Source : E. Coli or Yeast
Species : Mouse
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 375
Purity : >90%
Notes : Small volumes of Actg1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : Actg1 actin, gamma, cytoplasmic 1 [ Mus musculus ]
Official Symbol : Actg1
Synonyms : ACTG1; actin, gamma, cytoplasmic 1; actin, cytoplasmic 2; gamma-actin; beta-actin FE-3; E51; Actg; Actl; AL023024;
Gene ID : 11465
mRNA Refseq : NM_009609
Protein Refseq : NP_033739
Pathway : Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Bacte
Function : ATP binding; identical protein binding; nucleotide binding; protein binding; structural constituent of cytoskeleton;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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What is the role of ACTG1 in cellular processes? 04/27/2022

ACTG1 plays a crucial role in cytoskeletal dynamics, cell division, cell migration, and maintaining cell shape.

What is the role of ACTG1 mutation in humans? 04/26/2022

ACTG1 mutation leads to hearing loss in humans.

What do bioinformatics analyses reveal about the role of inflammatory response in IDD? 02/22/2021

GO function and pathway enrichment analysis suggest that inflammatory response plays a crucial role in IDD based on differentially expressed genes (DEGs) from microarray datasets.

Is ACTG1 associated with intervertebral disc degeneration (IDD)? 12/16/2020

Yes, bioinformatics analysis suggests that ACTG1 might be a hub gene in IDD.

What is the proposed role of ACTG1 in regulating the fitness of uterine cancer cells? 10/22/2020

 It is proposed that ACTG1 regulates the fitness of uterine cancer cells by modulating cell-intrinsic properties and the tumor microenvironment.

How does ACTG1 regulate the development of IDD? 08/12/2020

ACTG1 regulates the development of IDD through the NF-κB-p65 and Akt pathways.

What transcriptional patterns are associated with ACTG1 gains in uterine cancers? 12/27/2019

ACTG1 gains in uterine cancers are associated with transcriptional patterns reflecting activation of oncogenic signals, repression of response to innate immunity, or immunotherapy.

How is ACTG1 connected to inflammation-related pathways? 09/22/2019

In the protein-protein interaction (PPI) network, ACTG1 is connected to proteins involved in inflammation-related pathways.

How does the knockdown of ACTG1 affect tumor cells? 07/05/2019

The knockdown of ACTG1 suppresses the proliferation and migration of tumor cells.

Is the low expression of ACTG1 observed in animal models of intervertebral disc degeneration? 01/23/2019

Yes, the low expression of ACTG1 is also found in degenerated NP tissues in rats.

Can ACTG1 mutations be inherited? 09/10/2018

Yes, ACTG1 mutations can be inherited in an autosomal dominant pattern, which means that one copy of the mutated gene is sufficient to cause the condition.

What are the consequences of ACTG1 depletion in human NP cells? 08/26/2018

Depletion of ACTG1 in human NP cells increases MMP3 expression, decreases collagen II levels, and leads to excessive apoptosis, exacerbating IDD.

 How does ACTG1 compare to other actomyosin genes in terms of its functions in uterine cancer? 05/04/2018

ACTG1's functions relative to other actomyosin genes support the notion that it is a potential biomarker and a target gene in precision therapies for uterine cancer.

Could ACTG1 be a potential marker and therapeutic target for IDD? 02/21/2018

Yes, based on the findings, ACTG1 may serve as a novel marker and therapeutic target for IDD in the future.

Which type of cancer shows the highest frequencies of amplification and overexpression of the ACTG1 gene? 12/03/2017

Uterine cancers, including mixed endometrial carcinomas, serous carcinomas, endometroid carcinomas, and carcinosarcomas, have the highest frequencies of ACTG1 gene amplification or overexpression.

What is the clinical significance of ACTG1 gains in uterine cancers? 07/05/2017

Patients with ACTG1 gains in uterine cancers have a poor prognosis.

What is the function of the ACTG1 gene? 05/03/2017

The ACTG1 gene encodes the protein actin gamma-1, which is involved in cell structure and movement.

How does ACTG1 expression vary in degenerated intervertebral disc tissues? 06/21/2016

The expression of ACTG1 is low in severely degenerated nucleus pulposus (NP) tissues compared to mildly degenerated samples. The ACTG1 level is negatively correlated with human disc degeneration grades.

How does the deletion of ACTG1 using CRISPR-CAS9 gene editing affect uterine cancer cells? 05/15/2016

The deletion of ACTG1 using CRISPR-CAS9 gene editing has robust and consistent effects on uterine cancer cells, indicating its functional importance in these cells compared to 20 other lineages.

Are there any known diseases associated with ACTG1 mutations? 01/31/2016

Yes, mutations in ACTG1 have been linked to conditions such as Baraitser-Winter syndrome and nonsyndromic hearing loss.

Customer Reviews (5)

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Reviews
07/04/2022

    The functional assays using the protein product consistently yield strong and reproducible signals, indicating its high efficacy.

    01/08/2022

      The protein product was carefully packaged, with appropriate cold-chain shipping to maintain its stability and integrity.

      04/16/2020

        It shows remarkable lot-to-lot consistency, ensuring reliable and reproducible experimental outcomes.

        07/11/2019

          The protein product exhibits exceptional stability, maintaining its structural integrity even under challenging experimental conditions.

          11/10/2018

            The company's representatives were knowledgeable and provided valuable guidance on experimental protocols and optimization.

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