Recombinant Human DDX3Y, His-tagged

• Cat.No.: DDX3Y-3751H
• Product Overview: ATP-dependent RNA helicase DDX3Y (DDX3Y)

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 660
• Purity: >90%
• Notes: Small volumes of DDX3Y recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: DDX3Y DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [ Homo sapiens ]
• Official Symbol: DDX3Y
• Synonyms: DDX3Y; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; DBY, DEAD/H (Asp Glu Ala Asp/His) box polypeptide, Y chromosome; ATP-dependent RNA helicase DDX3Y; DEAD box protein 3, Y-chromosomal; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome; DBY
• Gene ID: 8653
• mRNA Refseq: NM_001122665
• Protein Refseq: NP_001116137
• MIM: 400010
• UniProt ID: O15523
• Chromosome Location: Yq11
• Pathway: RIG-I-like receptor signaling pathway, organism-specific biosystem; RIG-I-like receptor signaling pathway, conserved biosystem
• Function: ATP binding; ATP-dependent helicase activity; DNA binding; RNA binding; helicase activity; hydrolase activity; nucleotide binding