Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Mouse Il9, MIgG2a Fc-tagged, mutant

Cat.No. : Il9-001M
Product Overview : The extracellular domain of mouse IL-9 (NP_032399.1)(Gln19-Pro144) is fused to the N-terminus of the Fc region of mutant mouse IgG2a was expressed in CHO cell.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. Thiscytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor(IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokineto various biological processes. The gene encoding this cytokine has been identified as a candidate gene forasthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in thepathogenesis of bronchial hyperresponsiveness.
Source : CHO cell
Species : Mouse
Tag : MIgG2a Fc-tagged, mutant
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured in a cell proliferation assay.
Molecular Mass : 40KDa (monomer)
AA Sequence : Gln19-Pro144)
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : Il9 interleukin 9 [ Mus musculus ]
Official Symbol : Il9
Synonyms : IL9; interleukin 9; interleukin-9; cytokine P40; T-cell growth factor P40; P40; Il-9;
Gene ID : 16198
mRNA Refseq : NM_008373
Protein Refseq : NP_032399
Pathway : Asthma, organism-specific biosystem; Asthma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL-9 Signaling Pathway, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine activity; cytokine receptor binding; growth factor activity; interleukin-9 receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
How is the clinical trial of IL9 progressing? 09/05/2022

Several clinical trials are currently underway to evaluate the safety and effectiveness of IL9 in treating conditions such as asthma and allergies. However, the research is still in its early stages and more data are needed.

How to obtain IL9? 03/13/2022

IL9 can be synthesized in the laboratory by biotechnological methods. Before clinical use, it needs to go through strict quality control and testing.

What is the action mechanism of IL9? 09/22/2021

By binding to specific receptors, IL9 can activate relevant signaling pathways and regulate the development and function of immune cells. It can affect the activity of a variety of immune cells, such as T cells and macrophages.

Howthe relationship between IL9 and other related cytokines? 05/02/2020

IL9 has cross-action with other cytokines, which can regulate the expression and function of each other. For example, IL9 can promote the production of IL4 and IL13, and IL4 and IL13 can also promote the secretion of IL9.

What are the clinical applications of IL9? 09/26/2019

IL9 can be used to treat certain inflammatory diseases, such as asthma and skin allergies. It can regulate the response of the immune system and reduce the symptoms of related diseases.

What is the mechanism of action of IL9 in the treatment of asthma? 01/11/2019

The mechanism of action of IL9 in asthma treatment is not fully understood, but studies have shown that it can reduce the infiltration of inflammatory cells and the release of inflammatory mediators, thereby reducing the symptoms of asthma.

Customer Reviews (3)

Write a review
Reviews
08/04/2022

    The anti-interference ability of IL9 was excellent in Western blot, which avoided the interference problem in the experiment.

    04/14/2019

      This protein has high catalytic efficiency, high safety and high expression level, and is a precious resource in the field of scientific research.

      02/28/2019

        The reproducibility of IL9 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.

        Ask a Question for All Il9 Products

        Required fields are marked with *

        My Review for All Il9 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends