Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human Insulin Like Growth Factor-I, HIgG1 Fc-tagged, mutant

Cat.No. : IGF1-650H
Product Overview : The extracellular domain of human IGF-1(AAA52543.1)(Gly26-Met130) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene
Source : CHO cell
Species : Human
Tag : HIgG1 Fc-tagged, mutant
Form : Lyophilized from 0.2 μm-filtered solution in PBS.
Bio-activity : Measured in a serum-free cell proliferation assay.
Molecular Mass : 38KDa (monomer)
AA Sequence : Gly26-Met130
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100 μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : IGF1 insulin-like growth factor 1 (somatomedin C) [ Homo sapiens ]
Official Symbol : IGF1
Synonyms : IGF1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor 1; IGF1A; MGF; IGF-IA; IGF-IB; somatomedin-C; mechano growth factor; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; IGFI; IGF-I;
Gene ID : 3479
mRNA Refseq : NM_000618
Protein Refseq : NP_000609
MIM : 147440
UniProt ID : P05019
Chromosome Location : 12q23.2
Pathway : Adipogenesis, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem;
Function : growth factor activity; hormone activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; integrin binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (3)

Write a review
Reviews
04/23/2022

    Range of applications of IGF1 is breathtaking, and it can play its unique advantage in any field.

    08/18/2021

      The biological activity and high purity of the protein are impressive, which is why it is a trusted partner in the field of scientific research.

      06/13/2021

        IGF1 can preserve its stability under extreme conditions, such as at high or low temperatures, which is very beneficial for our experiments.

        Ask a Question for All IGF1 Products

        Required fields are marked with *

        My Review for All IGF1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends