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Recombinant Human Interleukin 33, HIgG1 Fc-tagged, mutant

Cat.No. : IL33-122H
Product Overview : The extracellular domain of human IL-33 (AAH47085.1)(Ser112-Thr270) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
Description : IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells
Source : CHO cell
Species : Human
Tag : HIgG1 Fc-tagged, mutant
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured in a cell proliferation assay.
Molecular Mass : 44KDa (monomer)
AA Sequence : Ser112-Thr270
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : IL33 interleukin 33 [ Homo sapiens ]
Official Symbol : IL33
Synonyms : IL33; interleukin 33; C9orf26, chromosome 9 open reading frame 26 (NF HEV); interleukin-33; DKFZp586H0523; DVS27; DVS27 related protein; IL1F11; interleukin 1 family; member 11; NF HEV; nuclear factor for high endothelial venules; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor from high endothelial venules; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2;
Gene ID : 90865
mRNA Refseq : NM_001199640
Protein Refseq : NP_001186569
MIM : 608678
UniProt ID : O95760
Chromosome Location : 9p24.1
Pathway : Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem;
Function : cytokine activity; protein binding;

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