"IL29" Related Products

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Recombinant Human IL29, HIgG1 Fc-tagged

Cat.No.: IL29-003H
Product Overview: The extracellular domain of human IL-29 (AAI17483.1)(Gly20-Thr200) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell.
Description: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Source: CHO cell
Species: Human
Tag: HIgG1 Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured in an anti-viral assay.
Molecular Mass: 46KDa (monomer)
AA Sequence: Gly20-Thr200
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: IL29 interleukin 29 (interferon, lambda 1) [ Homo sapiens ]
Official Symbol: IL29
Synonyms: IL29; interleukin 29 (interferon, lambda 1); interleukin 29; interleukin-29; IFNL1; IL 29; IFN-lambda-1; cytokine Zcyto21; interferon lambda-1; interferon-lambda-1; interferon, lambda 1; IL-29;
Gene ID: 282618
mRNA Refseq: NM_172140
Protein Refseq: NP_742152
MIM: 607403
UniProt ID: Q8IU54
Chromosome Location: 19q13.13
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function: cytokine activity; interleukin-28 receptor binding; receptor binding;

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