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Active Recombinant Mouse IL23, MIgG2a Fc-tagged, mutant

Cat.No. : IL23-155M
Product Overview : The mouse IL-23 complex composed of the p40 subunit (P43432)(aa 23-335) and the p19 subunit (Q9EQ14)(aa 20-196) is fused through a polypeptide linker to the Fc portion of a mutant mouse IgG2a was expressed in CHO cell.
  • Specification
  • Gene Information
  • Related Products
Source : CHO cell
Species : Mouse
Tag : MIgG2a Fc-tagged, mutant
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured in a cell proliferation assay using PHA-activated mouse splenocytes.
Molecular Mass : 85 KDa(monomer)
AA Sequence : The mouse IL-23 complex composed of the p40 subunit (P43432)(aa 23-335) and the p19 subunit (Q9EQ14)(aa 20-196) is fused through a polypeptide linker to the Fc portion of a mutant mouse IgG2a.
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : ≥98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : IL23
Official Symbol : IL23
Synonyms : IL23 ;interleukin 23
Gene ID : 100310803

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Does IL23 expression correlate with disease severity in psoriasis? 05/12/2022

IL23 expression correlates with disease severity in psoriasis.

Does IL23 expression vary between different immune cell types? 06/03/2021

IL23 expression varies among dendritic cells and macrophages.

What are the downstream targets of IL23 signaling? 07/24/2020

IL23 activates STAT3 to modulate downstream targets.

Does IL23 interact with other cytokines in a signaling cascade? 06/07/2019

IL23 interacts with IL-12 to form a signaling cascade.

Is IL23 involved in the activation of STAT3? 04/29/2019

IL23 is involved in the activation of STAT3.

How does IL23 expression change in autoimmune diseases? 10/02/2018

IL23 expression is upregulated in autoimmune diseases like Crohn's.

What is the half-life of IL23 in plasma? 01/14/2018

The half-life of IL23 in plasma is approximately 2 hours.

How does IL23 affect macrophage polarization? 10/25/2017

IL23 induces M1 macrophage polarization.

What is the role of IL23 in Th17 cell differentiation? 03/19/2017

IL23 promotes Th17 cell differentiation by activating STAT3.

How does IL23 contribute to tissue inflammation? 01/27/2016

IL23 contributes to tissue inflammation by activating macrophages.

Customer Reviews (3)

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Reviews
12/17/2021

    High purity levels in CHIP

    12/26/2018

      Effective in T-cell differentiation.

      09/25/2018

        Suitable for signaling studies.

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