Active Recombinant Mouse IL23, MIgG2a Fc-tagged, mutant
Cat.No. : | IL23-155M |
Product Overview : | The mouse IL-23 complex composed of the p40 subunit (P43432)(aa 23-335) and the p19 subunit (Q9EQ14)(aa 20-196) is fused through a polypeptide linker to the Fc portion of a mutant mouse IgG2a was expressed in CHO cell. |
- Specification
- Gene Information
- Related Products
Source : | CHO cell |
Species : | Mouse |
Tag : | MIgG2a Fc-tagged, mutant |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured in a cell proliferation assay using PHA-activated mouse splenocytes. |
Molecular Mass : | 85 KDa(monomer) |
AA Sequence : | The mouse IL-23 complex composed of the p40 subunit (P43432)(aa 23-335) and the p19 subunit (Q9EQ14)(aa 20-196) is fused through a polypeptide linker to the Fc portion of a mutant mouse IgG2a. |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | ≥98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionIL23 expression correlates with disease severity in psoriasis.
IL23 expression varies among dendritic cells and macrophages.
IL23 activates STAT3 to modulate downstream targets.
IL23 interacts with IL-12 to form a signaling cascade.
IL23 is involved in the activation of STAT3.
IL23 expression is upregulated in autoimmune diseases like Crohn's.
The half-life of IL23 in plasma is approximately 2 hours.
IL23 induces M1 macrophage polarization.
IL23 promotes Th17 cell differentiation by activating STAT3.
IL23 contributes to tissue inflammation by activating macrophages.
Customer Reviews (3)
Write a reviewHigh purity levels in CHIP
Effective in T-cell differentiation.
Suitable for signaling studies.
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