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Recombinant Human Interleukin 17F, HIgG1 Fc-tagged, mutant

Cat.No.: IL17F-366H
Product Overview: The extracellular domain of human IL-17F (AAH70124.1)(Arg31-Gln163) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
Description: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.
Source: CHO cell
Species: Human
Tag: HIgG1 Fc-tagged, mutant
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to induce IL-6 secretion.
Molecular Mass: 41KDa (monomer)
AA Sequence: Arg31-Gln163
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: IL17F interleukin 17F [ Homo sapiens ]
Official Symbol: IL17F
Synonyms: IL17F; interleukin 17F; interleukin-17F; IL 17F; ML 1; ML1; IL-24; cytokine ML-1; mutant IL-17F; interleukin-24; ML-1; CANDF6; IL-17F;
Gene ID: 112744
mRNA Refseq: NM_052872
Protein Refseq: NP_443104
MIM: 606496
UniProt ID: Q96PD4
Chromosome Location: 6p12
Pathway: IL23-mediated signaling events, organism-specific biosystem;
Function: cytokine activity; cytokine binding; protein homodimerization activity;

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