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Recombinant Human interleukin 17B, MIgG2a Fc-tagged

Cat.No.: IL17B-315H
Product Overview: The extracellular domain of human IL-17B(AAI13926.1)(Gln21-Phe180) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
Description: The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies
Source: CHO cell
Species: Human
Tag: MIgG2a Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to induce IL-8 secretion.
Molecular Mass: 44KDa (monomer)
AA Sequence: Gln21-Phe180
Endotoxin: <0.06 eu/μg as determined by lal>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: IL17B interleukin 17B [ Homo sapiens ]
Official Symbol: IL17B
Synonyms: IL17B; interleukin 17B; interleukin-17B; IL 17B; IL 20; MGC138900; MGC138901; neuronal interleukin 17 related factor; NIRF; ZCYTO7; interleukin 20; interleukin-20; cytokine Zcyto7; interleukin-17 beta; cytokine-like protein ZCYTO7; neuronal interleukin-17 related factor; neuronal interleukin-17-related factor; IL-20; IL-17B;
Gene ID: 27190
mRNA Refseq: NM_014443
Protein Refseq: NP_055258
MIM: 604627
UniProt ID: Q9UHF5
Chromosome Location: 5q33.1
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function: cytokine activity;

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