Active Recombinant Human IL12, HIgG1 Fc-tagged, mutant

• Cat.No.: IL12-002H
• Product Overview: The human IL-12 complex composed of the p40 subunit (NP_002178.2) (ILe23-Ser328) and the p35 subunit (NP_000873.2)(Arg57-Ser253) is fused through a polypeptide linker to the Fc region of a mutant human IgG1.

Specification

• Source: CHO cell
• Species: Human
• Tag: HIgG1 Fc-tagged, mutant
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured in a cell proliferation assay.
• Molecular Mass: 85KDa(monomer)
• AA Sequence: The human IL-12 complex composed of the p40 subunit (NP_002178.2) (ILe23-Ser328) and the p35 subunit (NP_000873.2)(Arg57-Ser253) is fused through a polypeptide linker to the Fc region of a mutant human IgG1.
• Endotoxin: <0.06 eu/μg as determined by lal test.>
• Purity: ≥98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: IL-12
• Official Symbol: IL12
• Synonyms: IL12; IL12B; IL-12B
• Gene ID: 100860848
• mRNA Refseq: NM_001285700
• Protein Refseq: NP_001272629
• UniProt ID: P68221
• Pathway: African trypanosomiasis, organism-specific biosystem;Allograft rejection, organism-specific biosystem;Chagas disease (American trypanosomiasis), organism-specific biosystem